ICI 204448

Ligand id: 1650

Name: ICI 204448

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 70.08
Molecular weight 464.13
XLogP 4.09
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Chen Y, Mestek A, Liu J, Yu L. (1993)
Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors.
Biochem. J., 295 ( Pt 3): 625-8. [PMID:8240267]
2. Yasuda K, Raynor K, Kong H, Breder CD, Takeda J, Reisine T, Bell GI. (1993)
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
Proc. Natl. Acad. Sci. U.S.A., 90 (14): 6736-40. [PMID:8393575]