Ligand id: 2456


Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 8
Rotatable bonds 8
Topological polar surface area 311.36
Molecular weight 506.01
XLogP -5.73
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Nilius B, Prenen J, Voets T, Droogmans G. (2004)
Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b.
Pflugers Arch., 448 (1): 70-5. [PMID:14758478]