AMP-PNP

Ligand id: 2456

Name: AMP-PNP

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 17
Hydrogen bond donors 8
Rotatable bonds 8
Topological polar surface area 311.36
Molecular weight 506.01
XLogP -5.73
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
TRPM4 Hs Gating inhibitor Antagonist 4.7 pIC50 - 1
pIC50 4.7 [1]
Voltage: 100.0 mV
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference