Ligand id: 3276

Name: guanylpirenzepine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 124.1
Molecular weight 379.18
XLogP 1.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Akbulut H, Gören Z, Iskender E, Eraslan A, Ozdemir O, Oktay S. (1999)
Subtypes of muscarinic receptors in rat duodenum: a comparison with rabbit vas deferens, rat atria, guinea-pig ileum and gallbladder by using imperialine.
Gen. Pharmacol., 32 (4): 505-11. [PMID:10323493]
2. Ferrari-Dileo G, Waelbroeck M, Mash DC, Flynn DD. (1994)
Selective labeling and localization of the M4 (m4) muscarinic receptor subtype.
Mol. Pharmacol., 46 (6): 1028-35. [PMID:7808421]
3. Waelbroeck M, De Neef P, Domenach V, Vandermeers-Piret MC, Vandermeers A. (1996)
Binding of the labelled muscarinic toxin 125I-MT1 to rat brain muscarinic M1 receptors.
Eur. J. Pharmacol., 305 (1-3): 187-92. [PMID:8813552]