Ligand id: 6475

Name: LY2886721

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 114.9
Molecular weight 390.1
XLogP 1.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. May P, Boggs L, Brier R, Calligaro D, Citron M, Day T, Lin S, Lindstrom T, Mergott D, Monk S et al.. (2012)
Preclinical characterizathion of LY2886721: A BACE1 inhibitor in clinical development for early Alzheimer's disease.
Alzheimer's and Dementia, 8 (4): 95.