LY2886721

Ligand id: 6475

Name: LY2886721

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 114.9
Molecular weight 390.1
XLogP 1.59
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
beta-secretase 1 Hs Inhibitor Competitive 7.7 pIC50 - 1
pIC50 7.7 (IC50 2.03x10-8 M) [1]