Synonyms: Amaryl® | glimepride | HOE-490 | Sugral®
glimepiride is an approved drug (FDA (1995))
Compound class:
Synthetic organic
Comment: Only approved by the EMA (2007) to be used in combination with pioglitazone (Tandemact®). Note that the PubChem CID listed above refers to the non-isomeric molecule. We show the isomeric form which corresponds to the structure held with the INN record for this compound.
View more information in the IUPHAR Pharmacology Education Project: glimepiride |
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References |
1. Inagaki N, Gonoi T, Clement 4th JP, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J. (1995)
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science, 270 (5239): 1166-70. [PMID:7502040] |
2. Miki T, Nagashima K, Seino S. (1999)
The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells. J Mol Endocrinol, 22 (2): 113-23. [PMID:10194514] |
3. Rehmann H. (2012)
Epac2: a sulfonylurea receptor?. Biochem Soc Trans, 40 (1): 6-10. [PMID:22260657] |