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Synonyms: pericyazine | propericiazine | RP-8909
periciazine is an approved drug (UK (2009))
Compound class: Synthetic organic
Comment: Periciazine is a phenothiazine antipsychotic. It has anti-dopaminergic, adrenolytic, anticholinergic, metabolic and endocrine effects.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Kanba S, Suzuki E, Nomura S, Nakaki T, Yagi G, Asai M, Richelson E. (1994)
Affinity of neuroleptics for D1 receptor of human brain striatum.
J Psychiatry Neurosci, 19 (4): 265-9. [PMID:7918347]
2. Tsukamoto T, Asakura M, Hirata N, Imafuku J, Matsui H, Hasegawa K. (1984)
Interaction of neuroleptics and antidepressants with rat brain alpha 2-receptors: a possible relationship between alpha 2-receptor antagonism and antidepressant action.
Biol Psychiatry, 19 (9): 1283-91. [PMID:6149771]