Ligand id: 9340

Name: PF-00547659

1. Pullen N, Molloy E, Carter D, Syntin P, Clemo F, Finco-Kent D, Reagan W, Zhao S, Kawabata T, Sreckovic S. (2009)
Pharmacological characterization of PF-00547659, an anti-human MAdCAM monoclonal antibody.
Br. J. Pharmacol., 157 (2): 281-93. [PMID:19366349]
2. Pullen N, Molloy E, Kellermann S-A, Green LL, Haak-Fredescho M. (2005)
Antibidies to MAdCAM.
Patent number: WO2005067620. Assignee: Pfizer Inc., Amgen Fremont Inc., Pfizer Limited. Priority date: 09/01/2004. Publication date: 27/07/2005.
3. Vermeire S, Sandborn WJ, Danese S, Hébuterne X, Salzberg BA, Klopocka M, Tarabar D, Vanasek T, Greguš M, Hellstern PA et al.. (2017)
Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial.
Lancet, 390 (10090): 135-144. [PMID:28527704]
4. Wang M, Kussrow AK, Ocana MF, Chabot JR, Lepsy CS, Bornhop DJ, O'Hara DM. (2017)
Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation.
Br. J. Pharmacol., 174 (1): 70-81. [PMID:27760281]