Synonyms: PF-00547659 | PF-547659 | SHP647
Compound class:
Antibody
Comment: Ontamalimab (PF-00547659) is a fully human, IgG2, investigational monoclonal antibody targeting mucosal addressin cell adhesion molecule 1 (MADCAM1) [1-2]. It is being evaluated for clinical potential in inflammatory bowel diseases. PF-00547659 was granted FDA orphan drug designation for ulcerative colitis in November 2017.
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Classification ![]() |
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Compound class | Antibody |
International Nonproprietary Names ![]() |
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INN number | INN |
10903 | ontamalimab |
Synonyms ![]() |
PF-00547659 | PF-547659 | SHP647 |
Database Links ![]() |
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Specialist databases | |
IMGT/mAb-DB | 785 |
Other databases | |
GtoPdb PubChem SID | 328083443 |
Search PubMed clinical trials | ontamalimab |
Search PubMed titles | ontamalimab |
Search PubMed titles/abstracts | ontamalimab |