compound 8c [PMID: 28760529]

Ligand id: 9671

Name: compound 8c [PMID: 28760529]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 102.73
Molecular weight 417.11
XLogP 2.95
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Yasui T, Yamamoto T, Sakai N, Asano K, Takai T, Yoshitomi Y, Davis M, Takagi T, Sakamoto K, Sogabe S et al.. (2017)
Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design.
Bioorg. Med. Chem., 25 (17): 4876-4886. [PMID:28760529]