frovatriptan   Click here for help

GtoPdb Ligand ID: 7191

Synonyms: Frova® | SB-209509-AX | VML-251
Approved drug
frovatriptan is an approved drug (FDA (2001))
Compound class: Synthetic organic
Comment: Frovatriptan is a triptan (tryptamine-based) drug.
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View more information in the IUPHAR Pharmacology Education Project: frovatriptan

2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 71.9
Molecular weight 243.14
XLogP 2.35
No. Lipinski's rules broken 0

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

SMILES / InChI / InChIKey
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Canonical SMILES CNC1Cc2c(CC1)[nH]c1c2cc(cc1)C(=N)O
Isomeric SMILES CN[C@H]1Cc2c(CC1)[nH]c1c2cc(cc1)C(=N)O
InChI InChI=1S/C14H17N3O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18)/t9-/m1/s1
InChI Key XPSQPHWEGNHMSK-SECBINFHSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)