cefteram   Click here for help

GtoPdb Ligand ID: 11051

Synonyms: cefterame | ceftetrame | CFTM | Ro 19-5247 | T-2525
Approved drug
cefteram is an approved drug (Japan)
Compound class: Synthetic organic
Comment: Cefteram is a semisynthetic, third generation cephalosporin (β-lactam) compound with broad-spectrum antibacterial activity. To provide acceptable bioavailability for oral use it is formulated as a pivoxil ester prodrug (cefteram pivoxil, T-2588, PubChem CID 5362114).
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 244.35
Molecular weight 479.08
XLogP -2.39
No. Lipinski's rules broken 1
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Canonical SMILES CO/N=C(\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)Cn1nnc(n1)C)/c1csc(n1)N
Isomeric SMILES CO/N=C(\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)Cn1nnc(n1)C)/c1csc(n1)N
InChI InChI=1S/C16H17N9O5S2/c1-6-20-23-24(21-6)3-7-4-31-14-10(13(27)25(14)11(7)15(28)29)19-12(26)9(22-30-2)8-5-32-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b22-9-/t10-,14-/m1/s1
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Molecular structure representations generated using Open Babel