cefteram

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Ligands
cefteram

GtoPdb Ligand ID: 11051

Synonyms: cefterame | ceftetrame | CFTM | Ro 19-5247 | T-2525

cefteram is an approved drug (Japan)

Comment: Cefteram is a semisynthetic, third generation cephalosporin (β-lactam) compound with broad-spectrum antibacterial activity. To provide acceptable bioavailability for oral use it is formulated as a pivoxil ester prodrug (cefteram pivoxil, T-2588, PubChem CID 5362114).

2D Structure

Physico-chemical Properties

Hydrogen bond acceptors	11
Hydrogen bond donors	3
Rotatable bonds	8
Topological polar surface area	244.35
Molecular weight	479.08
XLogP	-2.39
No. Lipinski's rules broken	1

SMILES / InChI / InChIKey

Canonical SMILES	CO/N=C(\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)Cn1nnc(n1)C)/c1csc(n1)N
Isomeric SMILES	CO/N=C(\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)Cn1nnc(n1)C)/c1csc(n1)N
InChI	InChI=1S/C16H17N9O5S2/c1-6-20-23-24(21-6)3-7-4-31-14-10(13(27)25(14)11(7)15(28)29)19-12(26)9(22-30-2)8-5-32-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b22-9-/t10-,14-/m1/s1
InChI Key	XSPUSVIQHBDITA-RKYNPMAHSA-N