CXCL4   Click here for help

GtoPdb Ligand ID: 3685

Synonyms: platelet factor 4 (PF4)
Immunopharmacology Ligand
Comment: CXCL4 is a C-X-C motif chemokine first identified in megakaryocytes and platelets. It is a potent antiangiogenic chemokine and also promotes inflammatory fibrosis [3]. It can be used as a prognostic marker for the fibrosing autoimmune disease systemic sclerosis (scleroderma) [2]. A CXCR3 splice variant, CXCR3B, is a functional receptor for CXCL4 [1].
Species: Human
Peptide Sequence Click here for help