tumour necrosis factor membrane form   

GtoPdb Ligand ID: 5073

Abbreviated name: TNF membrane form
Synonyms: cachectin | necrosin | TNFα
Comment: TNFα is a pro-inflammatory, acute phase cytokine involved in systemic inflammation.
The TNFSF2 precursor is also cleaved into a membrane-bound form of the ligand.
Species: Human
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Tumor necrosis factor superfamily ligands
Synonyms
cachectin | necrosin | TNFα
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
TNF tumor necrosis factor Human prepro-tumor necrosis factor DIF, TNFA, TNF-alpha, TNFSF2, TNF superfamily, member 2, tumor necrosis factor (TNF superfamily, member 2)
Database Links
CATH/Gene3D 2.60.120.40
DrugBank Target P01375 (Hs)
Ensembl Gene ENSG00000204490 (Hs)
GtoPdb PubChem SID 178101766
Human Protein Atlas ENSG00000204490 (Hs)
UniProtKB P01375 (Hs)
Wikipedia Tumor_necrosis_factor-alpha