Synonyms: WX-671
Compound class:
Synthetic organic
Comment: Upamostat (WX-671) is an oral serine protease inhibitor prodrug. Its principal molecular target is plasminogen activator, urokinase (uPA; PLAU) [2]. The uPA system plays an important role in tumour invasion and metastasis. The active substance is WX-UK1.
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Classification ![]() |
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Compound class | Synthetic organic |
Is prodrug? | Yes |
Active form | WX-UK1 |
IUPAC Name ![]() |
ethyl 4-[(2S)-3-{3-[(1E)-[(hydroxyamino)imino]methyl]phenyl}-2-[2,4,6-tris(propan-2-yl)benzenesulfonamido]propanoyl]piperazine-1-carboxylate |
International Nonproprietary Names ![]() |
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INN number | INN |
9416 | upamostat |
Synonyms ![]() |
WX-671 |
Database Links ![]() |
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CAS Registry No. | 590368-25-5 (source: PubChem) |
GtoPdb PubChem SID | 178103111 |
PubChem CID | 56843330 |
Search Google for chemical match using the InChIKey | CYCFEEXTLQGJEL-XEOXDSMQSA-N |
Search Google for chemicals with the same backbone | CYCFEEXTLQGJEL |
Search PubMed clinical trials | upamostat |
Search PubMed titles | upamostat |
Search PubMed titles/abstracts | upamostat |
UniChem Compound Search for chemical match using the InChIKey | CYCFEEXTLQGJEL-XEOXDSMQSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | CYCFEEXTLQGJEL-XEOXDSMQSA-N |