Synonyms: AGN-PC-0031SD | ARN-2966
Compound class:
Synthetic organic
Comment: 2-PMAP is an investigational compound for Alzheimer's disease (AD). A recent study has demonstrated that this compound crosses the blood-brain barrier and reduces levels of full-length amyloid precursor protein (APP) and amyloid beta (Aβ) deposition in the brains of AD model mice without causing significant toxicity [1]. This is accompanied by reduced Aβ pathology and rescue of memory deficit in AD model mice via an inhibitory effect on mRNA translation. This compound may exist as a tautomer with PubChem CID 68604369.
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Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
2-(pyridin-2-ylmethylamino)phenol |
Synonyms ![]() |
AGN-PC-0031SD | ARN-2966 |
Database Links ![]() |
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CAS Registry No. | 102212-26-0 (source: SciFinder) |
GtoPdb PubChem SID | 187051831 |
PubChem CID | 14936865 |
Search Google for chemical match using the InChIKey | GXJRVWZNMZGWAQ-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | GXJRVWZNMZGWAQ |
UniChem Compound Search for chemical match using the InChIKey | GXJRVWZNMZGWAQ-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | GXJRVWZNMZGWAQ-UHFFFAOYSA-N |