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Synonyms: AGN-PC-0031SD | ARN-2966
Compound class: Synthetic organic
Comment: 2-PMAP is an investigational compound for Alzheimer's disease (AD). A recent study has demonstrated that this compound crosses the blood-brain barrier and reduces levels of full-length amyloid precursor protein (APP) and amyloid beta (Aβ) deposition in the brains of AD model mice without causing significant toxicity . This is accompanied by reduced Aβ pathology and rescue of memory deficit in AD model mice via an inhibitory effect on mRNA translation. This compound may exist as a tautomer with PubChem CID 68604369.
|AGN-PC-0031SD | ARN-2966
|CAS Registry No.
|102212-26-0 (source: SciFinder)
|GtoPdb PubChem SID
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