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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide |
Synonyms ![]() |
compound 7c [PMID: 26396690] | JNJ63533054 |
Comments |
JNJ-63533054 is a small molecule agonist of GPR139 [1,3]. It is orally bioavailable and can cross the blood-brain barrier [4]. It is a surrogate ligand that can be used to examine GPR139 function in the absence of a validated endogenous ligand. Both PubChem (CID 4879329) and ChEMBL (CHEMBL1509813) record this compound with no specified stereochemistry. Patent WO2014152917 A2 describes the search for physiological ligands for GPR139 [2]. |
Database Links ![]() |
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BindingDB Ligand | 50132143 |
ChEMBL Ligand | CHEMBL3633720 |
GtoPdb PubChem SID | 252827424 |
PubChem CID | 2548547 |
Search Google for chemical match using the InChIKey | MWDVCHRYCKXEBY-LBPRGKRZSA-N |
Search Google for chemicals with the same backbone | MWDVCHRYCKXEBY |
Search UniChem for chemical match using the InChIKey | MWDVCHRYCKXEBY-LBPRGKRZSA-N |
Search UniChem for chemicals with the same backbone | MWDVCHRYCKXEBY |
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JNJ 63533054
Cat. No. 5666 |