Available chemical structures for TRPA1 activators

eugenol
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Targets
TRPA1; TRPV3
gingerol
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Targets
TRPA1
methyl salicylate
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Targets
TRPA1
icilin
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Targets
TRPA1; TRPM8
JT010
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Targets
TRPA1
PF-4840154
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Targets
TRPA1
cannabichromene
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Targets
TRPA1
dibenzoxazepine
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Targets
TRPA1
morphanthridine
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Targets
TRPA1
1'-acetoxychavicol acetate
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Targets
TRPA1
chlorobenzylidene malononitrile
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Targets
TRPA1
chloropicrin
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Targets
TRPA1
omega-chloroacetophenone
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Targets
TRPA1
NPPB
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Targets
CaCC; ClC-2; ClC-7; Maxi Cl-; TRPA1; VRAC
benzoquinone
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Targets
TRPA1
polygodial
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Targets
TRPA1
cannabidiol
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Targets
GPR18; GPR55; CB1 receptor; TRPA1; TRPM8; TRPV2; TRPV3
isovelleral
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Targets
TRPA1
ASP7663
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Targets
TRPA1
cannabigerol
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Targets
TRPA1; TRPM8
super cinnamaldehyde
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Targets
TRPA1
bromoacetone
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Targets
TRPA1
auranofin
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Targets
TRPA1
phytocannabinoid 6 [PMID: 38408345]
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Targets
TRPA1; TRPM8
allicin
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Targets
TRPA1; TRPV1
artepillin C
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Targets
TRPA1
4-oxo-nonenal
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Targets
TRPA1
nitrooleic acid
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Targets
TRPA1
1,6-hexamethylene diisocyanate
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Targets
TRPA1
N-acetyl-4-benzoquinoneimine
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Targets
TRPA1
oleocanthal
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Targets
TRPA1
2-pentenal
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Targets
TRPA1
acrolein
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Targets
TRPA1
salirasib
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Targets
TRPA1
cannabigeroquinone
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Targets
TRPA1; TRPM8
apomorphine
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Targets
α2A-adrenoceptor; α2B-adrenoceptor; α2C-adrenoceptor; 5-HT1A receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; D1 receptor; D2 receptor; D3 receptor; D4 receptor; D5 receptor; TRPA1
allyl isothiocyanate
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Targets
TRPA1
cannabidiolic acid
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Targets
TRPA1
Δ9-tetrahydrocannabinol
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Targets
GPR18; GPR55; CB1 receptor; CB2 receptor; TRPA1; TRPM8; TRPV2; glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor α3 subunit
benzyl bromide
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Targets
TRPA1
nicotine
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Targets
CYP2A6; Kv4.3; TRPA1; nicotinic acetylcholine receptor α10 subunit; nicotinic acetylcholine receptor α3 subunit; nicotinic acetylcholine receptor α4 subunit; nicotinic acetylcholine receptor α9 subunit
thymol
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Targets
TRPA1; TRPV3
URB597
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Targets
Fatty acid amide hydrolase; Fatty acid amide hydrolase-2; TRPA1
4-hydroxynonenal
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Targets
TRPA1
prostaglandin A2
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Targets
TRPA1
crotylaldehyde
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Targets
TRPA1
methyl isocyanate
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Targets
TRPA1
dibutyl phthalate
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Targets
TRPA1
docosahexaenoic acid
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Targets
FFA1 receptor; K2P10.1; Retinoid X receptor-α; TRPA1
(-)-menthol
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Targets
TRPA1; TRPM8; TRPV3
methylglyoxal
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Targets
TRPA1
cinnamaldehyde
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Targets
TRPA1; TRPV3
acetaldehyde
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Targets
TRPA1; TRPV6
flufenamic acid
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Targets
TAS2R14; Cx23; Cx25; Cx30.2; Cx43; Cx46; Cx59; Cx62; KNa1.2; Px1; TRPA1; TRPM2; TRPM4; TRPM5; TRPP2... click on ligand to see complete list
isoflurane
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Targets
K2P16.1; K2P2.1; K2P3.1; TRPA1
2-iodoacetamide
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Targets
TRPA1
formalin
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Targets
TRPA1
niflumic acid
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Targets
CaCC; ClC-1; ClC-Ka; ClC-Kb; Kv7.1; KNa1.2; TRPA1; TRPC4
NaHS
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Targets
TRPA1
MTSEA
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Targets
TRPA1
methyl p-hydroxybenzoate
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Targets
TRPA1

Please note that chemical structures may not be available for all activators at this target. For more details please email us.