H3 14s18 stapled B-chain   Click here for help

GtoPdb Ligand ID: 11910

Comment: This peptide is a stapled relaxin-3 mimetic [1-2]. It is a synthetic helical analogue of the relaxin-3 B chain. The hydrocarbon bond (staple) forms between the (S)2-(4′-pentenyl)alanine residues at positions 14 and 18.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP3 Hs Agonist Full agonist 7.5 pIC50 - 1-2
pIC50 7.5 [1-2]