INSL5   Click here for help

GtoPdb Ligand ID: 2000

Synonyms: insulin-like peptide 5
Species: Human
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Natural/Endogenous Targets
Target
RXFP3
RXFP4
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP4 Ligand is endogenous in the given species Hs Agonist Full agonist 7.3 – 8.8 pKi - 2,6-9
pKi 7.3 – 8.8 [2,6-9]
RXFP3 Ligand is endogenous in the given species Hs Antagonist Antagonist 7.0 pKi - 9
pKi 7.0 [9]
RXFP4 Ligand is endogenous in the given species Hs Agonist Full agonist 7.0 – 8.9 pEC50 - 1,3,6
pEC50 8.9 – 8.9 [3,6]
pEC50 7.0 – 7.7 [1]
RXFP4 Ligand is endogenous in the given species Hs Agonist Full agonist 8.3 – 8.9 pIC50 - 2,6-8
pIC50 8.3 – 8.9 [2,6-8]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields