Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference Solute carrier family 41 member 2 1

Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference Cav2.1 Rn Channel blocker - - - 1x10-4 - 1x10-3 8 ⤷ Conc range: 1x10-4 - 1x10-3 M [8] Voltage: -100.0 mV TRPP1 Hs Channel blocker - - - 1x10-4 5 ⤷ Conc range: 1x10-4 M [5] Voltage: 0.0 mV Cav3.2 Hs Channel blocker Pore blocker 4.9 – 5.2 pIC50 - 4 ⤷ pIC50 4.9 – 5.2 (IC50 1.2x10-5 – 5.7x10-6 M) [4] Voltage: -90.0 mV Cav2.3 Hs Channel blocker Antagonist 4.6 pIC50 - 7 ⤷ pIC50 4.6 (IC50 2.74x10-5 M) [7] Voltage: -90.0 mV Cav2.3 Rn Gating inhibitor Antagonist 3.6 – 4.7 pIC50 - 6,8 ⤷ pIC50 3.6 – 4.7 [6,8] Voltage: -100.0 mV Cav3.3 Rn Channel blocker Antagonist 3.7 – 4.1 pIC50 - 4 ⤷ pIC50 3.7 – 4.1 (IC50 2.16x10-4 – 8.7x10-5 M) [4] Voltage: -90.0 mV Cav3.1 Rn Channel blocker Antagonist 3.6 – 3.8 pIC50 - 4 ⤷ pIC50 3.6 – 3.8 (IC50 2.5x10-4 – 1.67x10-4 M) [4] Voltage: -90.0 mV CatSper1 Mm Channel blocker Inhibition 3.5 pIC50 - 3 ⤷ pIC50 3.5 (IC50 3x10-4 M) [3] Description: Whole cell patch clamp CatSper2 Mm Channel blocker Antagonist 3.5 pIC50 - 2 ⤷ pIC50 3.5 (IC50 3x10-4 M) [2] Description: Whole cell patch clamp. CatSper3 Mm Channel blocker Antagonist 3.5 pIC50 - 3 ⤷ pIC50 3.5 (IC50 3x10-4 M) [3] Description: Whole cell patch clamp electrophysiology. CatSper4 Mm Channel blocker Antagonist 3.5 pIC50 - 3 ⤷ pIC50 3.5 (IC50 3x10-4 M) [3] Description: Whole cell patch clamp electrophysiology. TRPC3 Hs Channel blocker - - - - ⤷