VPC32183

Ligand id: 2908

Name: VPC32183

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 25
Topological polar surface area 127.79
Molecular weight 602.35
XLogP 8.32
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
LPA1 receptor Hs Antagonist Antagonist 7.8 pKi - 1
pKi 7.8 [1]
LPA1 receptor Mm Antagonist Antagonist 7.0 pIC50 - 1
pIC50 7.0 (IC50 1.09x10-7 M) [1]
LPA3 receptor Hs Antagonist Antagonist 6.8 pIC50 - 1
pIC50 6.8 [1]
pIC50 6.8 (IC50 1.75x10-7 M) [1]