N-palmitoylethanolamine

Ligand id: 3622

Name: N-palmitoylethanolamine

Abbreviated name: PEA

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 17
Topological polar surface area 49.33
Molecular weight 299.28
XLogP 6.65
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Natural/Endogenous Targets
Target
GPR119
GPR55
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
GPR55 Hs Agonist Agonist 8.4 pEC50 - 2
pEC50 8.4 (EC50 4x10-9 M) [2]
GPR119 Hs Agonist Full agonist - - -
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference