indapamide   Click here for help

GtoPdb Ligand ID: 7203

Synonyms: Hypen SR® | Lozol®
Approved drug
indapamide is an approved drug (FDA (1983))
Compound class: Synthetic organic
Comment: Indapamide is a thiazide diuretic drug.
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: indapamide

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 100.88
Molecular weight 365.06
XLogP 2.39
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES CC1Cc2c(N1NC(=O)c1ccc(c(c1)S(=O)(=O)N)Cl)cccc2
Isomeric SMILES CC1Cc2c(N1NC(=O)c1ccc(c(c1)S(=O)(=O)N)Cl)cccc2
InChI InChI=1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)
Bioactivity Comments
Due to the polypharmacology of this drug, and the paucity of human affinity data, we do not tag a primary drug target.