Ligand id: 722

Name: L-citrulline

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 118.44
Molecular weight 175.1
XLogP -3.91
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Natural/Endogenous Targets
GPRC6 receptor
Enzymes Catalysing Reactions with this Compound as a Substrate or Product
Enzyme EC number Reaction Reference
Endothelial NOS
Inducible NOS
Neuronal NOS
Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Mitochondrial ornithine transporter 1 1
Mitochondrial ornithine transporter 2 1
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
GPRC6 receptor Hs Agonist Full agonist 3.6 pEC50 - 2
pEC50 3.6 [2]
Ligand mentioned in the following text fields