navarixin

Ligand id: 8497

Name: navarixin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 111.88
Molecular weight 397.16
XLogP 3.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CXCR2 Hs Antagonist Antagonist 10.3 pIC50 - 1-2
pIC50 10.3 (IC50 4.9x10-11 M) [1-2]
CXCR1 Hs Antagonist Antagonist 8.4 pIC50 - 1-2
pIC50 8.4 (IC50 3.9x10-9 M) [1-2]