anakinra   Click here for help

GtoPdb Ligand ID: 6972

Synonyms: antril | Kineret®
Approved drug Immunopharmacology Ligand
anakinra is an approved drug (FDA (no history prior to 2001), EMA (2002))
Comment: This drug is a recombinant, nonglycosylated form of the endogenous IL-1 receptor antagonist peptide with an additional methionine at the amino terminus compared to the endogenous peptide.
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Immunopharmacology Comments
Reduces the action of elevated IL-1 observed in rheumatoid arthritis.
Immunopharmacology Disease
Disease X-Refs Comment References
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
An IL-1RA mimetic approved to treat RA that is resistant to other anti-rheumatic drugs.