|
Molecular properties generated using the CDK |
Immunopharmacology Comments |
CC-220 is a novel cereblon-binding immunomodulator [3], functionally akin to lenalidomide and pomalidomide. |
Immunopharmacology Disease | |||
Disease | X-Refs | Comment | References |
Systemic lupus erythematosus |
Disease Ontology:
DOID:9074 OMIM: 152700 Orphanet: ORPHA536 |
Phase 2 clinical candidate for SLE- see NCT03161483 | |
Multiple myeloma |
Disease Ontology:
DOID:9538 OMIM: 254500 |
Phase 1/2 clinical candidate for MM- see NCT03161483 |