acipimox   Click here for help

GtoPdb Ligand ID: 1596

Synonyms: Olbetam®
Approved drug
acipimox is an approved drug (UK (2003))
Compound class: Synthetic organic
Comment: Acipimox is a nicotinic acid derivative.
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View more information in the IUPHAR Pharmacology Education Project: acipimox

2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 77.13
Molecular weight 154.04
XLogP -2.06
No. Lipinski's rules broken 0
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Canonical SMILES [O-][n+]1cc(ncc1C)C(=O)O
Isomeric SMILES [O-][n+]1cc(ncc1C)C(=O)O
InChI InChI=1S/C6H6N2O3/c1-4-2-7-5(6(9)10)3-8(4)11/h2-3H,1H3,(H,9,10)
1. Soga T, Kamohara M, Takasaki J, Matsumoto S, Saito T, Ohishi T, Hiyama H, Matsuo A, Matsushime H, Furuichi K. (2003)
Molecular identification of nicotinic acid receptor.
Biochem Biophys Res Commun, 303 (1): 364-9. [PMID:12646212]
2. Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A et al.. (2003)
Molecular identification of high and low affinity receptors for nicotinic acid.
J Biol Chem, 278 (11): 9869-74. [PMID:12522134]