GM-CSF   Click here for help

GtoPdb Ligand ID: 4942

Synonyms: colony-stimulating factor | CSF
Immunopharmacology Ligand
Comment: GM-CSF as a target in inflammatory/autoimmune disease was reviewed by Hamilton (2015) [2].
Species: Human
1. Bebbington CR, Yarranton GT. (2011)
Methods of treating heart failure using an anti-GM-CSF antibody.
Patent number: US8075885 B2. Assignee: Kalobios Pharmaceuticals, Inc.. Priority date: 01/12/2015. Publication date: 13/12/2011.
2. Hamilton JA. (2015)
GM-CSF as a target in inflammatory/autoimmune disease: current evidence and future therapeutic potential.
Expert Rev Clin Immunol, 11 (4): 457-65. [PMID:25748625]
3. Holgate ST. (2000)
Epithelial damage and response.
Clin. Exp. Allergy, 30 Suppl 1: 37-41. [PMID:10849473]
4. Krinner EM, Raum T, Petsch S, Bruckmaier S, Schuster I, Petersen L, Cierpka R, Abebe D, Mølhøj M, Wolf A et al.. (2007)
A human monoclonal IgG1 potently neutralizing the pro-inflammatory cytokine GM-CSF.
Mol. Immunol., 44 (5): 916-25. [PMID:16697465]
5. Sass PM, Nicolaides NE, Grasso L, Li J, Chao Q, Routhier E, Ebel W. (2007)
Antigenic gm-csf peptides and antibodies to gm-csf.
Patent number: WO2007092939. Assignee: Morphotek, Inc.. Priority date: 08/02/2006. Publication date: 16/08/2007.
6. Steidl S, Thomassen-Wolf E. (2006)
Anti-gm-csf antibodies and uses therefor.
Patent number: WO2006122797A2. Assignee: Morphosys Ag. Priority date: 18/05/2005. Publication date: 23/11/2006.
7. Uddin M, Lau LC, Seumois G, Vijayanand P, Staples KJ, Bagmane D, Cornelius V, Dorinsky P, Davies DE, Djukanović R. (2013)
EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma.
PLoS ONE, 8 (9): e72502. [PMID:24039773]