Ligand id: 9705

Name: AM2201

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 22
Molecular weight 359.17
XLogP 6.92
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Banister SD, Stuart J, Kevin RC, Edington A, Longworth M, Wilkinson SM, Beinat C, Buchanan AS, Hibbs DE, Glass M et al.. (2015)
Effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135.
ACS Chem Neurosci, 6 (8): 1445-58. [PMID:25921407]
2. Hutter M, Moosmann B, Kneisel S, Auwärter V. (2013)
Characteristics of the designer drug and synthetic cannabinoid receptor agonist AM-2201 regarding its chemistry and metabolism.
J Mass Spectrom, 48 (7): 885-94. [PMID:23832945]
3. Järbe TUC, Raghav JG. (2017)
Tripping with Synthetic Cannabinoids ("Spice"): Anecdotal and Experimental Observations in Animals and Man.
Curr Top Behav Neurosci, 32: 263-281. [PMID:27753006]
4. Makriyannis A, Deng H. (2001)
Cannabimimetic indole derivatives.
Patent number: WO2001028557. Assignee: University Of Connecticut. Priority date: 18/10/1999. Publication date: 26/04/2001.
5. Tournebize J, Gibaja V, Kahn JP. (2017)
Acute effects of synthetic cannabinoids: Update 2015.
Subst Abus, 38 (3): 344-366. [PMID:27715709]