Synonyms: AC0137 | Symlin®
pramlintide is an approved drug (FDA (2005))
Compound class:
Peptide
Comment: Pramlintide is an analogue of human amylin, with prolines replacing the native amino acids at positions 25, 28 and 29. The marketed medicine is the acetate salt (PubChem CID 16132446). ChEMBL also represents the acetate form with the record CHEMBL1201669.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖View more information in the IUPHAR Pharmacology Education Project: pramlintide |
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Other Similar Sequences | |
amylin {Sp: Human} |
TargetsAM1 receptor; AM2 receptor; AMY1 receptor; AMY2 receptor; AMY3 receptor; CGRP receptor; CT receptor |
amylin {Sp: Mouse, Rat} |
TargetsAMY1 receptor; AMY2 receptor; AMY3 receptor; CT receptor |
[125I]BH-AMY (rat, mouse) |
TargetsAMY1 receptor; AMY2 receptor; AMY3 receptor |