CXCL8   Click here for help

GtoPdb Ligand ID: 821

Synonyms: interleukin-8
Immunopharmacology Ligand
Comment: The CXCL8 (IL-8) chemokine is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. It can form homodimers and heterodimers with CXCL4.
Species: Human
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Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Synonyms Click here for help
interleukin-8
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
CXCL8 C-X-C motif chemokine ligand 8 Human interleukin 8 3-10C, alveolar macrophage chemotactic factor I, AMCF-I, b-ENAP, beta endothelial cell-derived neutrophil activating peptide, chemokine (C-X-C motif) ligand 8, CXCL8, GCP-1, GCP1, granulocyte chemotactic protein 1, IL-8, IL8, interleukin 8, K60, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, LYNAP, MDNCF, MONAP, monocyte-derived neutrophil-activating peptide, monocyte-derived neutrophil chemotactic factor, NAF, NAP-1, NAP1, neutrophil-activating peptide 1, SCYB8, TSG-1, tumor necrosis factor-induced gene 1
Database Links Click here for help
Specialist databases
GPCRdb Ligand CXCL8
Other databases
Ensembl Gene ENSG00000169429 (Hs)
GtoPdb PubChem SID 135651725
Human Protein Atlas ENSG00000169429 (Hs)
Immunopaedia Search CXCL8
UniProtKB P10145 (Hs)
Wikipedia Interleukin_8