orexin-A   Click here for help

GtoPdb Ligand ID: 1697

Synonyms: hypocretin-1
Species: Human, Mouse, Rat
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Natural/Endogenous Targets
Target
OX1 receptor
OX2 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
OX1 receptor Ligand is endogenous in the given species Hs Agonist Full agonist 6.5 – 10.2 pEC50 - 1-9,11-16,18-19
pEC50 6.5 – 10.2 [1-9,11-16,18-19]
OX2 receptor Ligand is endogenous in the given species Hs Agonist Full agonist 6.5 – 10.0 pEC50 - 1,3,5,10-11,13-15,17,20
pEC50 6.5 – 10.0 [1,3,5,10-11,13-15,17,20]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields