C5a

Ligand id: 573

Name: C5a

Species: Human

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
C3a receptor
C5a1 receptor
C5a2 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
C5a2 receptor Hs Agonist Full agonist 8.9 pEC50 -
pEC50 8.9 (EC50 1.4x10-9 M)
C5a1 receptor Hs Agonist Full agonist 8.0 – 9.0 pEC50 - 6,8
pEC50 8.0 – 9.0 (EC50 1x10-8 – 1x10-9 M) [6,8]
C5a1 receptor Hs Agonist Full agonist 9.1 – 9.2 pIC50 - 4,8
pIC50 9.1 – 9.2 [4,8]
C5a2 receptor Hs Agonist Full agonist 8.0 – 8.6 pIC50 - 2,7
pIC50 8.0 – 8.6 (IC50 9.5x10-9 – 2.5x10-9 M) [2,7]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields