K-252a

Ligand id: 336

Name: K-252a

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 94.72
Molecular weight 467.15
XLogP 5.34
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

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Similar Ligands
KT 5720
Targets
M1 receptor; M4 receptor
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Targets
M1 receptor; M2 receptor
staurosporine
Targets
M1 receptor; M2 receptor; M4 receptor; TRAF2 and NCK interacting kinase; calcium/calmodulin-dependent protein kinase II beta subunit; death associated protein kinase 1; homeodomain interacting protein kinase 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 6; p21 (RAC1) activated kinase 2; phosphorylase kinase catalytic subunit gamma 2; protein kinase C iota; protein kinase N1; protein kinase, cAMP-dependent, catalytic, beta subunit; serine/threonine kinase 3... click on ligand to see complete list
lestaurtinib
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fms related receptor tyrosine kinase 3
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fms related receptor tyrosine kinase 3
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3-phosphoinositide dependent protein kinase 1; LCK proto-oncogene, Src family tyrosine kinase; checkpoint kinase 1; checkpoint kinase 2; cyclin dependent kinase 1; glycogen synthase kinase 3 beta; microtubule affinity regulating kinase 1; mitogen-activated protein kinase 14; protein kinase A; protein kinase C alpha; protein kinase C beta; protein kinase C delta; protein kinase C epsilon; protein kinase C gamma
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mitogen-activated protein kinase kinase kinase 10; mitogen-activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 9