codeine   Click here for help

GtoPdb Ligand ID: 1673

Synonyms: Codicept® | methylmorphine
Approved drug
codeine is an approved drug (FDA (no history prior to 2009))
Comment: Codeine is an opioid analgesic related to, but less potent than morphine.
Marketed formulations may contain codeine sulfate (PubChem CID 6098421).
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: codeine

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 41.93
Molecular weight 299.15
XLogP 0.81
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES COc1ccc2c3c1OC1C43CCN(C(C2)C4C=CC1O)C
Isomeric SMILES COc1ccc2c3c1O[C@@H]1[C@@]43CCN([C@H](C2)[C@@H]4C=C[C@@H]1O)C
InChI InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1
InChI Key OROGSEYTTFOCAN-DNJOTXNNSA-N

For advanced searching click here to open chemical structure editor

Similar Ligands Click here for help
[3H]diprenorphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
dihydromorphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
diprenorphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
etorphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
morphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
nalmefene
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
nalorphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
normorphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
β-FNA
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
BNTX
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
naloxone
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
naltrexone
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
nalfurafine
Click here for ligand page
Targets
κ receptor
nalbuphine
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
naloxone benzoylhydrazone
Click here for ligand page
Targets
κ receptor; μ receptor
(+)-naloxone
Click here for ligand page
Targets
κ receptor
buprenorphine
Click here for ligand page
Targets
κ receptor; μ receptor
[3H]naloxone
Click here for ligand page
Targets
μ receptor
naloxonazine
Click here for ligand page
Targets
μ receptor
hydrocodone
Click here for ligand page
Targets
κ receptor; μ receptor
hydromorphone
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
oxycodone
Click here for ligand page
oxymorphone
Click here for ligand page
naloxegol
Click here for ligand page
methylnaltrexone
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
dihydrocodeine
Click here for ligand page
diamorphine
Click here for ligand page
pholcodine
Click here for ligand page
BU08028
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor; NOP receptor
BU72
Click here for ligand page
Targets
μ receptor
MP1104
Click here for ligand page
Targets
κ receptor
NFP
Click here for ligand page
Targets
δ receptor; κ receptor; μ receptor
oxycodegol
Click here for ligand page
Targets
δ receptor; μ receptor