staurosporine

Ligand id: 346

Name: staurosporine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 69.45
Molecular weight 466.2
XLogP 6.05
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

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Similar Ligands
K-252a
Targets
Calmodulin-dependent kinase II; M1 receptor
KT 5720
Targets
M1 receptor; M4 receptor
KT 5823
Targets
M1 receptor; M2 receptor
lestaurtinib
Targets
fms related tyrosine kinase 3
midostaurin
Targets
fms related tyrosine kinase 3
7-hydroxystaurosporine
Targets
3-phosphoinositide dependent protein kinase 1; LCK proto-oncogene, Src family tyrosine kinase; checkpoint kinase 1; checkpoint kinase 2; cyclin dependent kinase 1; glycogen synthase kinase 3 beta; microtubule affinity regulating kinase 1; mitogen-activated protein kinase 14; protein kinase A; protein kinase C alpha; protein kinase C beta; protein kinase C delta; protein kinase C epsilon; protein kinase C gamma
CEP-1347
Targets
mitogen-activated protein kinase kinase kinase 10; mitogen-activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 9