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Synonyms: Adrenergic toxin rho-elapitoxin-Dp1b | rho-EPTX-Dp1b
Compound class:
Peptide or derivative
Comment: This peptide is a toxin component of black mamba (Dendroaspis polylepis) venom [2]. Its sequence diverges from that of muscarinic toxin β by only two amino acids in its C-terminal. CM-3 has antagonist properties at mammalian adrenoceptors [1].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Other Similar Sequences  |
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| muscarinic toxin 1 |
TargetsM1 receptor; M4 receptor |
| muscarinic toxin 2 |
TargetsM1 receptor; M4 receptor |
| muscarinic toxin 3 |
Targetsα2A-adrenoceptor; M1 receptor; M2 receptor; M3 receptor; M4 receptor; M5 receptor |
| muscarinic toxin 7 |
TargetsM1 receptor; M2 receptor; M3 receptor; M4 receptor; M5 receptor |
| ρ-Da1a |
Targetsα1A-adrenoceptor |
| muscarinic toxin β |
Targetsα1B-adrenoceptor |
