zaragozic acid A

Ligand id: 3057

Name: zaragozic acid A

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 14
Hydrogen bond donors 5
Rotatable bonds 19
Topological polar surface area 223.42
Molecular weight 690.29
XLogP 4.26
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

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Similar Ligands
10-OBn-7α-F-gingkolide B
Targets
PAF receptor
10-OBn-ginkgolide B
Targets
PAF receptor
10-OBn-ginkgolide C
Targets
PAF receptor
10-OBn-epi-ginkgolide C
Targets
PAF receptor
7α-Cl-ginkgolide B
Targets
PAF receptor
7α-F-ginkgolide B
Targets
PAF receptor
7α-N3-ginkgolide B
Targets
PAF receptor
7α-NH2-ginkgolide B
Targets
PAF receptor
7α-NHEt-ginkgolide B
Targets
PAF receptor
7α-NHMe-ginkgolide B
Targets
PAF receptor
7α-OAc-ginkgolide B
Targets
PAF receptor
7α-OCOCH2Ph-ginkgolide B
Targets
PAF receptor
7-epi-ginkgolide C
Targets
PAF receptor
ginkgolide A
Targets
Glycine Receptor (All subtypes); PAF receptor
ginkgolide B
Targets
5-HT3A; 5-HT3AB; Glycine Receptor (All subtypes); PAF receptor; glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor α3 subunit; glycine receptor β subunit
ginkgolide C
Targets
Glycine Receptor (All subtypes); PAF receptor
ginkgolide J
Targets
Glycine Receptor (All subtypes); PAF receptor
picrotoxinin
Targets
5-HT3A; 5-HT3AB; Glycine Receptor (All subtypes); glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor α3 subunit; glycine receptor β subunit
bilobalide
Targets
5-HT3A; 5-HT3AB; Glycine Receptor (All subtypes); glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor β subunit
zaragozic acid C
Targets
squalene synthase
compound 5d [PMID: 7966163]
Targets
squalene synthase
compound 6c [PMID: 7966163]
Targets
squalene synthase
compound 6d [PMID: 7966163]
Targets
squalene synthase
compound 4e [PMID: 7966163]
Targets
squalene synthase
compound 5d [PMID: 7966163]
Targets
squalene synthase
compound 16a [Sharratt et al., 1994]
Targets
squalene synthase
compound 3f [PMID: 7966163]
Targets
squalene synthase
L-735021
Targets
squalene synthase
compound 6g [PMID: 7966163]
Targets
squalene synthase
picrotoxin
Targets
5-HT3A; 5-HT3AB; GABAA receptor α3 subunit; GABAA receptor α5 subunit; GABAA receptor α6 subunit; GABAA receptor β1 subunit; GABAA receptor β3 subunit; GABAA receptor δ subunit; GABAA receptor γ2 subunit; GABAA receptor ρ1 subunit; GABAA receptor ρ2 subunit; GABAA receptor ρ3 subunit; glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor β subunit... click on ligand to see complete list
1,9-dideoxyforskolin
Targets
VRAC
picrotin
Targets
glycine receptor α1 subunit; glycine receptor α2 subunit; glycine receptor α3 subunit; glycine receptor β subunit
carboxyatractyloside
Targets
Mitochondrial adenine nucleotide translocator 1
forskolin
zaragozic acid B
Targets
squalene synthase
tirotundin
Targets
Peroxisome proliferator-activated receptor-γ
tagitinin A
Targets
Peroxisome proliferator-activated receptor-γ
compound 45 [PMID: 8709105]
Targets
adenylyl cyclase 1
artemisinin
Targets
null
FD1
Targets
adenylyl cyclase 2
FD6
Targets
adenylyl cyclase 5