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Synonyms: MG531 | Nplate®
romiplostim is an approved drug (FDA (2008), EMA (2009))
Compound class:
Peptide
Comment: This drug is a thrombopoietin receptor agonist, although its peptide sequence does not resemble that of the endogenous peptide thrombopoietin. Romiplostim is known as a peptibody, a fusion between the Fc portion of immunoglobulin and a therapeutic peptide. In this case the drug exists as a heterodimer. The carboxy terminal 14 amino acid residues of this peptibody constitute the thrombopoietin receptor binding domain (single letter amino acid code: IEGPTLRQWLAARA).
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Other Similar Sequences  |
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| rilonacept |
Targetsnull |
| abatacept |
TargetsCD80; CD86 |
| belatacept |
TargetsCD80; CD86 |
| trebananib |
Targetsnull |
| resokine | |
| efgartigimod alfa |
TargetsFc fragment of IgG receptor and transporter |
| luspatercept |
Targetsnull |
| MK-7110 |
Targetssialic acid binding Ig like lectin 10 |
| inbakicept | |
| sotatercept |
Targetsnull |
| efzofitimod | |
