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Synonyms: example 9 [US11518759]
Compound class:
Synthetic organic
Comment: This compound is claimed as a PROTAC that targets coronavirus 3CL protease (Mpro) for degradation, in patent US11518759 [1]. It uses a VHL-based ligand to direct the bound Mpro protein to the E3 ubiquitin ligase complex.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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