5'-inosine monophosphate

Ligand id: 5124

Name: 5'-inosine monophosphate

Abbreviated name: 5'-IMP

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 5
Rotatable bonds 4
Topological polar surface area 189.83
Molecular weight 348.05
XLogP -1.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

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Similar Ligands
4-thio-UTP
Targets
P2Y2 receptor
5BrUTP
Targets
P2Y2 receptor; P2Y6 receptor
MRS2698
Targets
P2Y2 receptor
uridine triphosphate
Targets
P2Y11 receptor; P2Y2 receptor; P2Y4 receptor; P2Y6 receptor
UTPγS
Targets
P2Y2 receptor; P2Y4 receptor
diquafosol
Targets
P2Y2 receptor; P2Y4 receptor
denufosol
Targets
P2Y2 receptor; P2Y4 receptor
(N)methanocarba-UTP
Targets
P2Y4 receptor
CTP
Targets
P2Y4 receptor
guanosine-5'-triphosphate
Targets
Kir6.1; P2Y4 receptor; Vesicular nucleotide transporter
ITP
Targets
P2Y4 receptor
3-phenacyl-UDP
Targets
P2Y6 receptor
INS48823
Targets
P2Y6 receptor
MRS2693
Targets
P2Y6 receptor
MRS2782
Targets
P2Y6 receptor
uridine diphosphate
Targets
GPR17; Kir6.1; P2Y14 receptor; P2Y6 receptor
UDP-β-S
Targets
P2Y6 receptor
Up3U
Targets
P2Y6 receptor
UDP N-acetyl-glucosamine
Targets
P2Y14 receptor; UDP-N-acetylglucosamine transporter; UDP-galactose transporter; YEA
UDP-galactose
Targets
GPR17; P2Y14 receptor; UDP-galactose transporter
UDP-glucose
Targets
GPR17; P2Y14 receptor
UDP-glucuronic acid
Targets
P2Y14 receptor; UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter
cyclic GMP
Targets
CNGA1; CNGA2; CNGA3; HCN2; HCN4; phosphodiesterase 10A; phosphodiesterase 11A; phosphodiesterase 2A; phosphodiesterase 3A; phosphodiesterase 3B; phosphodiesterase 4D; phosphodiesterase 5A; phosphodiesterase 7A; phosphodiesterase 7B; phosphodiesterase 8B... click on ligand to see complete list
guanosine 5'-diphosphate
Targets
Kir6.1; Vesicular nucleotide transporter
cADPR
Targets
TRPM2
saxitoxin
Targets
Nav1.1; Nav1.2; Nav1.3; Nav1.4; Nav1.5; Nav1.6; Nav1.7
MRS2690
Targets
P2Y14 receptor
2-thioUTP
Targets
P2Y2 receptor
MRS2768
Targets
P2Y2 receptor
MRS4062
Targets
P2Y4 receptor
GTPγS
Targets
Maxi Cl-; VRAC
TNP-ATP
Targets
P2X1; P2X3
NBTGR
Targets
Equilibrative nucleoside transporter 1
inosine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 2; Solute carrier family 28 member 3
uridine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium-dependent nucleobase transporter; Sodium/nucleoside cotransporter 1; Solute carrier family 28 member 3
guanosine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 2; Solute carrier family 28 member 3
GDP-fucose
Targets
GDP-Fucose transporter
5-fluorouridine
Targets
Solute carrier family 28 member 3
CMP-sialic acid
Targets
CMP-sialic acid transporter
thymidine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 1; Sodium/nucleoside cotransporter 2; Solute carrier family 28 member 3
cytidine
Targets
Equilibrative nucleoside transporter 1; Sodium/nucleoside cotransporter 1; Solute carrier family 28 member 3
zebularine
Targets
Equilibrative nucleoside transporter 3; Solute carrier family 28 member 3
UDP-xylose
Targets
YEA
UDP-N-acetylgalactosamine
Targets
HFRC1; UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter
gemcitabine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Sodium/nucleoside cotransporter 1; Solute carrier family 28 member 3; ribonucleotide reductase catalytic subunit M1; ribonucleotide reductase regulatory subunit M2
floxuridine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 3; Solute carrier family 28 member 3
pentostatin
Targets
Adenosine deaminase; Equilibrative nucleoside transporter 1
zidovudine
Targets
Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 1; Solute carrier family 28 member 3
cytarabine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2
zalcitabine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 1; Solute carrier family 28 member 3
didanosine
Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 2; Solute carrier family 28 member 3
loxoribine
Targets
TLR7
poly(I:C)
Targets
TLR3
2'-deoxyinosine
5'-dGMP
Targets
Ecto-5'-Nucleotidase
5'-GMP
Targets
Ecto-5'-Nucleotidase
5'-UMP
Targets
Ecto-5'-Nucleotidase
acadesine
Targets
AMP kinase
Rp-8-CPT-cGMPS
Targets
Protein kinase G (PKG) 1
GDPβS
PSB1114
Targets
P2Y2 receptor
MRS2957
Targets
P2Y6 receptor
MRS2905
Targets
P2Y14 receptor
MRS2802
Targets
P2Y14 receptor
Rp-5-OMe-UDPαB
Targets
P2Y6 receptor
MRS2927
Targets
P2Y4 receptor
N4-phenylethoxycytidine-5'-triphosphate
Targets
P2Y4 receptor
2-amino-uridine-5'-monophosphate
Targets
P2Y4 receptor
2-thio-UDP
Targets
P2Y14 receptor
α.β-methylene-2-thio-UDP
Targets
P2Y14 receptor
cyclic CMP
Targets
HCN2
azacitidine
capecitabine
Targets
thymidylate synthetase
decitabine
ribavirin
Targets
Equilibrative nucleoside transporter 1; Sodium/nucleoside cotransporter 1; inosine monophosphate dehydrogenase 1; inosine monophosphate dehydrogenase 2
nelarabine
sofosbuvir
acelarin
trifluridine
PSB-6426
Targets
ectonucleoside triphosphate diphosphohydrolase 2
MRS4162
Targets
P2Y6 receptor
MRS4183
Targets
P2Y14 receptor
agatolimod
Targets
TLR9