cyclic GMP   Click here for help

GtoPdb Ligand ID: 2347

Abbreviated name: cGMP
Synonyms: 3',5'-cyclic GMP | 3',5'-guanosine monophosphate | cyclic guanosine monophosphate
PDB Ligand
Compound class: Metabolite
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 10
Hydrogen bond donors 4
Rotatable bonds 1
Topological polar surface area 184.62
Molecular weight 345.05
XLogP -2.44
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OC1C2OP(=O)(O)OCC2OC1n1cnc2c1nc(N)[nH]c2=O
Isomeric SMILES O[C@@H]1[C@@H]2OP(=O)(O)OC[C@H]2O[C@H]1n1cnc2c1nc(N)[nH]c2=O
InChI InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1
InChI Key ZOOGRGPOEVQQDX-UUOKFMHZSA-N

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Similar Ligands Click here for help
fomivirsen
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stimulator of interferon response cGAMP interactor 1
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TLR7
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agatolimod
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P2Y14 receptor
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P2Y4 receptor
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P2Y14 receptor
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P2Y6 receptor
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P2Y2 receptor
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Targets
Ecto-5'-Nucleotidase
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Targets
Ecto-5'-Nucleotidase
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Targets
Ecto-5'-Nucleotidase
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Targets
Ecto-5'-Nucleotidase
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poly(I:C)
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TLR3
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TLR7
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Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 2; Solute carrier family 28 member 3
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Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 1; Solute carrier family 28 member 3
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Targets
Adenosine deaminase; Equilibrative nucleoside transporter 1
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Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 3; Solute carrier family 28 member 3
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HFRC1; UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter
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YEA
thymidine
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Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 1; Sodium/nucleoside cotransporter 2; Solute carrier family 28 member 3
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Solute carrier family 28 member 3
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GDP-Fucose transporter
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Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium-dependent nucleobase transporter; Sodium/nucleoside cotransporter 1; Solute carrier family 28 member 3
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Targets
Equilibrative nucleoside transporter 1; Equilibrative nucleoside transporter 2; Equilibrative nucleoside transporter 3; Sodium/nucleoside cotransporter 2; Solute carrier family 28 member 3
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Maxi Cl-; VRAC
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P2Y4 receptor
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P2Y2 receptor
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P2Y2 receptor
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P2Y14 receptor
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TRPM2
guanosine 5'-diphosphate
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Kir6.1; Vesicular nucleotide transporter
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Targets
P2Y14 receptor; UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter
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Targets
GPR17; P2Y14 receptor
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Targets
GPR17; P2Y14 receptor; UDP-galactose transporter
UDP N-acetyl-glucosamine
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Targets
P2Y14 receptor; UDP-N-acetylglucosamine transporter; UDP-galactose transporter; YEA
Up3U
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Targets
P2Y6 receptor
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P2Y6 receptor
UDP
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GPR17; Kir6.1; P2Y14 receptor; P2Y6 receptor
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P2Y6 receptor
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P2Y6 receptor
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P2Y6 receptor
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P2Y6 receptor
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P2Y4 receptor
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Kir6.1; P2Y4 receptor; Vesicular nucleotide transporter
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P2Y4 receptor
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P2Y4 receptor
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P2Y2 receptor; P2Y4 receptor
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P2Y2 receptor; P2Y4 receptor
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P2Y2 receptor; P2Y4 receptor
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P2Y2 receptor
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P2Y2 receptor; P2Y6 receptor
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P2Y2 receptor