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The IUPHAR/BPS Guide to PHARMACOLOGY complete ligand list

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Antibacterial ligands
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Ligand name ID Synonyms
A Back to top
A2315A 10846
acorafloxacin 10753 avarofloxacin (former name), JNJ-Q2, JNJQ2
afabicin 10754 AFN-1720, Debio 1450, Debio1450
AHPN 3431 CD 437, CD437, Ro 47-2077
alafosfalin PDB Ligand 9503 alaphosphin
alalevonadifloxacin 10756 WCK 2349, WCK-2349, WCK2349
alpibectir 12957 BVL-GSK098
Altromycin B 10964
amifloxacin 10758 compound 7 [PMID: 2834557], WIN 49, 375, WIN 49,375-3, WIN-49375, WIN49375
amikacin Approved drug PDB Ligand 10894 Amikin®, AMK, Arikayce liposomal®, BB-K8
amoxicillin Approved drug 10895 Amoxil®, BRL-2333, co-amoxiclav (amoxicillin + clavulanic acid), Moxatag®, NSC-277174, Trimox®
ampicillin Approved drug PDB Ligand 10896 aminobenzylpenicillin, KS-R1, Penbritin®, Polycillin, Principen®
AN0128 10983 AN 0128, AN-0128, compound 2g [PMID: 16997550]
ANT3310 12795
apalcillin 10759 PC-904, PC904, WY-44,417, WY-44417
apramycin PDB Ligand 10760 EBL-1003, EL-857, EL857, nebramycin factor 2, nebramycin II
arachidonic acid PDB Ligand 2391 C20:4
arbekacin Approved drug PDB Ligand 7345 arbekacin sulfate, habekacin, ME1100, NPC-14
aspoxicillin Approved drug 12293 Doyle®, TA-058
avibactam Approved drug PDB Ligand 10761 AVI, NXL 104, NXL-104, NXL104
avibactam tomilopil 12949 ARX-1796, AV-006, PF-07338233
azidamfenicol Approved drug 12397 azidamphenicol, azidoamfenicol, azidoamphenicol, Thilocof®
azidocillin 12291 BRL 2534, SPC 297 D
azithromycin Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6510
azlocillin Approved drug 12260 Azlin®, BAY-E-6905
aztreonam Approved drug 10763 Azactam®, Cayston®, SQ 26776, SQ-26776, SQ26776
 
B Back to top
bacampicillin Approved drug 12292 Penglobe®, Spectrobid®
bacitracin A Approved drug 12812
BAL19403 10981 BAL 19403, BAL-19403
BAL30072 11004 BAL-30072
BAS-118 10976 BAS118, compound 7n [PMID: 11728192]
BC-3205 10998
BC-7013 11034 BC7013
bedaquiline Approved drug PDB Ligand 11171 BDQ, compound 1a [PMID: 17496888], R-207910, Sirturo®, TMC-207, TMC207
bederocin PDB Ligand 10764 REP-8839, REP8839
bekanamycin Approved drug PDB Ligand 12182 kanamycin B, nebramycin V
benapenem 12793
besifloxacin Approved drug 12877 Besivance®, BOL-303224-A, ISV-403, SS734
beta-defensin 4A  {Sp: Human} 3648 beta-defensin 2, HBD2, skin-antimicrobial peptide 1 (SAP1)
biapenem Approved drug 12022 L-627, LJC10,627, Omegacin®, RPX2003
BLI-489 free acid 10995 BLI489
bluensomycin 10765 bluensin, U-12898, U12898
borrelidin Antimalarial Ligand 11306 (-)-borrelidin
BRL-42715 10993 C6-(N1-Methyl-1,2,3-trazolylmethylene)penem, LS-186900 (sodium salt), LS-187554
BRL-44154 11036 analogue 4f [Brown et al., 1991], BRL44154
brodimoprim 12325 Ro 10-5970
BTZ-043 13034 BTZ-10526043, MMV676603
butikacin 10766 UK-18,892, UK-18892, UK18892
BWC0977 12809
 
C Back to top
cadazolid PDB Ligand 10767 ACT-179811, ACT179811
caffeic acid PDB Ligand 5155
carbenicillin Approved drug 10768 BRL-2064, BRL2064, carboxybenzylpenicillin, CBPC, CP 15639-2, CP-156392, Pyopen®
carfecillin Approved drug 12288 BRL 3475, carbenicillin phenyl, Uticillin®
carindacillin Approved drug 12276 carbenicillin indanyl, CP-15,464-2, CP-15464-2, Geocillin®
carumonam Approved drug 12296 AMA-1080, Ro 17-2301
cationomycin 11002 BRN-6263205, BRN6263205, LS-52659, LS52659
CB-182804 11003 CB-182,804, CB182804
cefacetrile 12192 Celospor®, cephacetrile
cefaclor Approved drug 10897 Ceclor®, Lilly 99638, Raniclor®
cefadroxil Approved drug 4831 Duricef®
cefaloglycin Approved drug 12193 cephaloglycin, Kafocin®
cefaloridine 12189 cephaloridine, ceporin
cefalotin Approved drug PDB Ligand 8798 cephalothin, cephalotin, Keflin®
cefamandole Approved drug PDB Ligand 12210 cephamandole
cefapirin Approved drug 12191 Cefadyl®, cephapirin
cefatrizine 12204 BL-S640
cefazaflur 10770 SK&F 59962
cefazedone 12203 EMD-30087, Refosporen®
cefazolin 10935 Ancef®, cephazolin, CEZ, Kefzol®, SK&F-41558
cefbuperazone 12253
cefcapene Approved drug 12053 Flomox® (cefcapene pivoxil), S-1006
cefclidin 10771 cefclidine, E-1040, E1040
cefdinir Approved drug 12023 FK 482, Omnicef®
cefditoren Approved drug 12030 ME 1206, Spectracef® (cefditoren pivoxil)
cefepime Approved drug 10772 BMY-28142, BMY28142, CFPM, Maxipime®, Renapime®
cefetamet 12416 Ro 15-8074
cefetecol 10775 GR-69153, GR-69153X, GR69153
cefiderocol Approved drug 10776 compound 3 [PMID: 29960205], Fetcroja®, Fetroja®, GSK-2696266, GSK2696266, RSC 649266, RSC-649266, RSC649266, S-649266
cefixime Approved drug PDB Ligand 10898 (E)-Cefixime, Cefspan®, CFIX, FK-027, FR-17027, Suprax®
cefluprenam 10777 E-1077, E1077
cefmatilen 10778 S-1090, S1090
cefmenoxime Approved drug 12024 A-50912, Abbott 50192, Bestron®, Cefmax®, SCE-1365
cefmetazole Approved drug PDB Ligand 12215 CS-1170, U-72791, Zefazone®
cefminox 12255 MT 141
cefodizime 12032 HR 221
cefonicid Approved drug 12217 Monocid®, SK&F 75073
cefoperazone Approved drug 12025 Cefobid®, T-1551
ceforanide Approved drug 12218 BL-S786, Precef®
cefoselis Approved drug 12034 FK-037, Wincef®
cefotaxime Approved drug PDB Ligand 10893 Claforan®, Ru-24756
cefotetan Approved drug 10936 Apatef®, Cefotan®, ICI-156834, ICI156834
cefotiam 12254 SCE 963
cefoxitin Approved drug PDB Ligand 10937 Cenomycin®, CFX, Mefoxin®, MK-306, MK306
cefozopran Approved drug 12054 SCE-2787
cefpimizole 10779 CPIZ, U 63196E, U-63,196, U-63196E
cefpiramide Approved drug 12027 SM-1652, WY-44635
cefpirome Approved drug 12033 HR 810, Romecef®
cefpodoxime Approved drug 10780 RU-51746, Vantin®
cefprozil Approved drug 12219 BMY-28100, Cefzil®
cefsulodin 10783 Cefonomil®, CGP-7174-E, CGP7174/E
ceftaroline fosamil Approved drug 10899 PPI-0903, TAK-599, Teflaro®, Zinforo®
ceftazidime Approved drug 10762 CAZ, Fortaz®, Fortum®, GR 20263, GR-20263, GR20263, LY-139381, LY139381, Pentacef®, Tazicef®
cefteram Approved drug 11051 cefterame, ceftetrame, CFTM, Ro 19-5247, T-2525
ceftezole 12259 ceftezol, FR10123
ceftibuten Approved drug 12029 7432-S, Cedax®, SCH 39720
ceftiolene 10784 42980RP, cefatiolene, RP 42,980, RP 42980, RP-42980, RP42980
ceftizoxime Approved drug 10785 Cefizox®, compound 22 {PMID: 2342058], Epocelin®, FK-749, FK749, FR-13749, FR13749, SK&F 88373-Z
ceftizoxime alapivoxil 10786 AS-924, AS924, KY-020, KY020
ceftobiprole Approved drug 10787 BAL-9141, BAL9141, BAL9141-000, BAL9141000, Ro-63-9141, Ro-639141, Zeftera®, Zevtera®
ceftolozane Approved drug 10788 CXA-101, CXA101, FR-264205, FR264205, Zerbaxa® (ceftolozane + tazobactam)
ceftriaxone Approved drug 5326 Rocephin®
cefuroxime Approved drug PDB Ligand 10900 Ceftin®, CXM, Kefurox®, Zinacef®
cephalexin Approved drug 4832 cefalexin, Ceporex®, Keflex®
cephalosporin P1 12330 acremonic acid
cephradine Approved drug 4830 cefradine, Infexin®, Velocef®
cetefloxacin 10790 compound 43f [PMID: 7990118], E-4868, E4868
cethromycin PDB Ligand 10791 A-195773, Abbott-195773, ABT-773, ABT773, Restanza®
cetocycline 10792 A-40728, Abbott 40728, chelocardin, compound 1 [PMID: 379332]
CG-400549 PDB Ligand 10984 CG400549
CGP-31608 10963 CGP 31608, CGP31608
chalcomycin 11058
chinfloxacin 11017
chloramphenicol Approved drug PDB Ligand 10901 Brolene®, chloromycetin
chlorocardicin 11044
chrysin PDB Ligand 8789 NSC-407436
cilastatin Approved drug 5166 MK 0791, MK-791, MK791, Primaxin®
cinoxacin Approved drug 12401 Cinobac®, Lilly 64716
ciprofloxacin Approved drug PDB Ligand 10902 BAY-O-9867, BAY-O9867, Cetraxal®, Ciloxan®, Cipro®, CPFX, Proquin XR
CJ-15,801 Antimalarial Ligand 10610 CJ-15801
cladosporin PDB Ligand Antimalarial Ligand 10247 asperentin
clarithromycin Approved drug PDB Ligand 10903 6-O-methylerythromycin, A-56268, ABBOTT-56268, Biaxin®, Klaricid®, TE-031
clavulanic acid Approved drug PDB Ligand 11128 BRL-14151, BRL-14151K, BRL14151, clavulanate, MM 14151
clinafloxacin 10793 AM 1091, CI-960, PD-127321
clindamycin Approved drug PDB Ligand Antimalarial Ligand 10607
clofazimine Approved drug Immunopharmacology Ligand 9184 Lamprene®
clofoctol Approved drug 12926 Gramplus®, Octofene®
clometocillin 12294 clometacillin, clomethacillin
clorobiocin PDB Ligand 12127 chlorobiocin, RP 18,631
cloxacillin Approved drug PDB Ligand 11126 BRL-1621, BRL1621, chloroxacillin, Methocillin S, Syntarpen®, Tegopen®
colistin Approved drug 10794 Colobreathe®, polymyxin E, Promixin®
compound 5 [Stecula et al., 2020] 11155 MCULE-2879769428
contezolid Approved drug PDB Ligand 10795 MRX-1, MRX-I, Youxitai®
contezolid acefosamil (parent) 10796 MRX-4
Corallopyronin A 11029 CorA, LS-54950, LS54950
coumamycin PDB Ligand 10879 coumermycin A1, notomycin
CRS3123 PDB Ligand 10991 CRS-3123, REP-3123, REP3123
cyclacillin Approved drug 4817 ciclacillin, Cyclapen®, Vastcillin®, Wy-4508
cyclothialidine 10988 Ro 09-1437
 
D Back to top
dactimicin 11001 Formimidoyl-fortimicin A, SF-2052, SF2052
dalbavancin Approved drug 10876 BI-397, BI397, Dalvance®, Xydalba®
dalfopristin Approved drug PDB Ligand 10797 RP-54476, RP54476, Synercid® (dalfopristin + quinupristin)
danirixin Immunopharmacology Ligand 8500 GSK-1325756B, GSK1325756, GSK1325756B
dapsone Approved drug Antimalarial Ligand 10934 Aczone®, NSC-6091
daptomycin Approved drug 10904 Cubicin®, LY-146032, LY146032
DC-159a 10982
D-cycloserine Approved drug PDB Ligand 9489 Seromycin®
DEBIO 1452 10755 afabicin desphosphono, AFN-1252, AFN-12520000, DEBIO-1452, DEBIO1452
decaplanin 10968 M 861410, M86-1410, MM-47761
declovanillobiocin 12128 novclobiocin 313
delafloxacin Approved drug 10799 Abbott 492, ABT-492, ABT492, Baxdela®, Quofenix®
delamanid Approved drug 12876 Deltyba®, OPC-67683
delpazolid 10999 LCB-01,0371, LCB-01-0371, LCB01-0371
demeclocycline 10905 Declomycin®, Ledermycin®
diacerein Approved drug 10800 Artrodar®, Fisiodar®
dibekacin Approved drug PDB Ligand 12134 3',4'-dideoxykanamycin B, debecacin
dicloxacillin Approved drug 12261 BRL-1702, Diclocil®, Dynapen®
difficidin 11062
difloxacin 10801 A 56619, A-56619, Dicural®
dihydrostreptomycin Approved drug PDB Ligand 12163
dihydroxybenzofuran 10992 2,3-Benzofurandiol
dirithromycin Approved drug PDB Ligand 12928 AS-E 136, Dynabac®, LY237216
DK-507k 11037
doripenem Approved drug PDB Ligand 12183 compound 1m [PMID: 8621362], Doribax®, S-4661
doxycycline Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6464 BMY-28689, Monodox®, Vibramycin®
DS-8587 10955 DS8587
DS-2969b 10985 DS 11960558 (DS-2969b prodrug), DS-2969, example 2 [WO2017/056012A1]
Dup-105 10950 DuP 105, DuP105
DuP-721 10960 DuP 721
durlobactam Approved drug 12693 ETX-2514, EXT2514, Xacduro® (sulbactam and durlobactam)
DX-619 11039 compound 4 [PMID: 19736016], DX619
 
E Back to top
E-0702 11056
ecenofloxacin 10802 CFC-222, CFC222
E-1010 free base 11050 E1010, ER-35786
Enduracidin 10989
enmetazobactam 12188 AAI101, OCID-5090
enoxacin Approved drug 8882 AT-2266, CI-919, Penetrex®
enteromycin carboxamide 11063 BRN 2416858, BRN-2416858, BRN2416858, LS-14645
eperezolid 10803 comound 2 [PMID: 23584544], PNU-100592, PNU100592, U-100592, U100592
epicillin 10804 Dexacillin®, SQ 11302, SQ-11302, SQ11302
epiroprim 12327 Ro 11-8958, TCMDC-137295
eravacycline Approved drug PDB Ligand 10805 compound 17j [PMID: 2148514], TP-434, TP434, Xerava®
eremomycin 10959 A82846A
ertapenem Approved drug 10906 Invanz®, L-749345, MK-0826, MK-826
erythromycin Approved drug PDB Ligand 1456 EM-A, E-Mycin®, Erythrocin®, erythromycin-A
ethambutol Approved drug PDB Ligand 12996 Myambutol®
etheromycin 10994 CP‐38 295
ethionamide Approved drug PDB Ligand 12954 1314 TH, Bayer 5312, Trecator®
ethyl bromopyruvate 10952
ETX0282 10781 ETX-0282
ETX0462 PDB Ligand 11753 ETX-0462, VMM
ETX1317 10782 ETX-1317
evernimicin 10806 SCH 27899, SCH-27899, SCH27899, Ziracin®
evybactin 12922 GLXC-26146
 
F Back to top
fandofloxacin 10807 DW-116, DW116
faropenem PDB Ligand 10808 compound 1 [PMID: 9216830], faropenem medoxomil, fropenem
feldamycin 10979 BMY-28565, BMY28565, U-48266
Ferrimycin A1 10966
ficellomycin 10965 U-47,929, U-47929, U47929
fidaxomicin Approved drug PDB Ligand 10909 Dificid®, Dificlir®, lipiarmycin, OPT-80, PAR-101, tiacumicin B
finafloxacin 10809 AL-60371, AL60371, Xtoro®
fleroxacin Approved drug 12476 AM-833, Megalone®, Quinodis®, Ro 23-6240
flomoxef 12251 6315-S, Flumarin®
florfenicol 12923 SCH 25298
flucloxacillin Approved drug 10910 BRL-2039, BRL2039, floxacillin
fludalanine 10810 3-fluoro-D-alanine, MK-0642, MK0642
flurithromycin Approved drug 12927 (8S)-8-fluoroerythromycin A, P-0501A
fosfomycin Approved drug PDB Ligand 10813 Monurol®, phosphomycin, phosphonomycin, Veramina®
fosmidomycin PDB Ligand Antimalarial Ligand 9739 FR-31564
furagin Approved drug 12367 furazidin, furazidine, NF416
furazolidone Approved drug 12343 Furoxone®
furazolium 10814 Novofur
fusidic acid Approved drug PDB Ligand 10815 CEM-102, CEM102, Fucidin®, fusidate, sodium fusidate, Taksta®
 
G Back to top
ganfeborole 12796 GSK3036656, GSK656
garenoxacin Approved drug 12402 BMS-284756, Ganefloxacin, Garenfloxacin, Geninax®, T-3811
gatifloxacin Approved drug 10816 AM-1155, AM1155, Gatiflo®, GTFX, Tequin®, Zymar®
gemifloxacin Approved drug 12406 Factive®, LB20304, SB 265805
gentamicin Approved drug 2427 Garamycin®, gentamicin sulfate
gepotidacin PDB Ligand 10817 GSK-2140944, GSK2140944
gloximonam 10880 SQ 82,531
grepafloxacin Approved drug 10818 OPC 17116, OPC-17116, OPC17116, Raxar®
 
H Back to top
hedamycin 10958 antibiotic B 26,158, B26158, NSC-70929
helvolic acid 12329 fumigacin
hesperetin PDB Ligand 10953 3',5,7-Trihydroxy-4'-methoxyflavanone, NP-13, NSC-57654
hetacillin Approved drug 12263
hexachlorophene Approved drug PDB Ligand 11069 Inh 1 [PMID: 32284327], Nabac®
ω-Hydroxyemodin 11005 Citreorosein, omega-Hydroxyemodin
hymeglusin 5886 antibiotic 1233A, F-244, L-659,699
 
I Back to top
ibafloxacin 10819 R-835, R835, S-25930, S25930
ibezapolstat 11030 ACX-362E, ACX362E
iboxamycin 11790 IBX, OPP-3
iclaprim 10820 AR-100, AR100, Mersarex®, RO-48-2622, RO-482622
imipenem Approved drug 10821 MK-0787, MK0787, Primaxin® (imipenem + cilastatin), Recarbrio® (imipenem + cilastatin + relebactam).
indanomycin 10949 X-14547A
indolmycin PDB Ligand Antimalarial Ligand 11021 PA 155 A, PA-155-A, PA-155A, TAK-083
Irresistin-16 10973 IRS-16, IRS16
iseganan 10822 IB-367, IB-367-03
isepamicin Approved drug 12136 HAPA-B, Sch 21420
isoniazid Approved drug PDB Ligand 12761 isonicotinic acid hydrazide, Nydrazid®, Rimifon®
isovanillobiocin 12129 novclobiocin 312
IT-62-B 11032
ivermectin Approved drug 2373 Heartgard®, ivermectin B1a, MK-933, Sklice®, Soolantra®
 
J Back to top
josamycin Approved drug 12924 kitasamycin A3, leucomycin A3, turimycin A5
 
K Back to top
kaempferol PDB Ligand 11052 Robigenin
kanamycin Approved drug PDB Ligand 12132 kanamycin A
Katanosin B 10970 Lysobactin
KB-5246 11046 KB5246, LS-99630
kibdelomycin A 11016
 
L Back to top
L-701677 11042 L-701,677
L-708365 10980 L 708,365, L 708365,