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The IUPHAR/BPS Guide to PHARMACOLOGY complete ligand list

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Ligands specifically tagged as being of relevance to immunopharmacology & the Guide to IMMUNOPHARMACOLOGY.
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Ligand name ID Synonyms
A Back to top
852A Immunopharmacology Ligand 9025
A286982 Immunopharmacology Ligand 6592 A 286982, A-286982
A438079 Immunopharmacology Ligand 4118 A 438079, A-438079
AB928 PDB Ligand Immunopharmacology Ligand 11154 AB-928
abatacept Approved drug Immunopharmacology Ligand 6891 BMS-188667, CTLA4-IgG4m, Orencia®, RG-1046, RG-2077
ABBV-3373 Immunopharmacology Ligand 12917 ADC 122
abediterol Immunopharmacology Ligand 9326 LAS-100977
AbGn-168H Immunopharmacology Ligand 10013 AbGn-168, neihulizumab
abrezekimab Immunopharmacology Ligand 9806 CDP7766, UCB-4144, UCB4144, VR-942
abrilumab Immunopharmacology Ligand 11531 AMG 181, AMG-181, MEDI-7183, MEDI7183
abrocitinib Approved drug PDB Ligand Immunopharmacology Ligand 9991 Cibinqo®, compound 25 [PMID: 29298069], PF-04965842, PF04965842
abscisic acid Immunopharmacology Ligand 10362 (+/-)-(cis,trans)-abscisic acid, (+/-)-Abscisic acid, (RS)-Abscisic acid, ABA
ABT-737 PDB Ligand Immunopharmacology Ligand 8320 ABT 737, ABT737, compound 2 [PMID 17256834]
AC430 Immunopharmacology Ligand 9177 AC-430
acalabrutinib Approved drug PDB Ligand Immunopharmacology Ligand 8912 ACP-196, Calquence®, Example 6 [US20140155385 A1]
Ac-SDKP Immunopharmacology Ligand 10060 goralatide, seraspenide
ACT-1014-6470 Immunopharmacology Ligand 12326 example 172 [WO2019137927A1], Ic-58
ACT-389949 Immunopharmacology Ligand 9511
ACT-660602 Immunopharmacology Ligand 12207 ACT660602, compound 9j [PMID: 35947786]
ACT-777991 Immunopharmacology Ligand 12584 ACT777991, compound 8a [PMID: 36883854]
ACTH  {Sp: Human} Approved drug Immunopharmacology Ligand 3633 Acthar®, adrenocorticotropic hormone (1-39), corticotropin
acumapimod Immunopharmacology Ligand 9203 BCT 197, BCT-197, BCT197, compound A [WO2013139809]
adalimumab Approved drug Immunopharmacology Ligand 4860 D2E7, Humira®
(-)-adrenaline Approved drug PDB Ligand Immunopharmacology Ligand 479 adrenalin, Auvi-Q®, Epipen®, l-adrenaline, L-epinephrine, levoepinephrine
adrenomedullin  {Sp: Human} Immunopharmacology Ligand 683 AM
adriforant Immunopharmacology Ligand 8985 PF 3893787, PF-03893787, ZPL-389, ZPL-3893787, ZPL389, ZPL3893787
ADU-S100 Immunopharmacology Ligand 10192 dithio-(Rp,Rp)-[cyclic[A(2',5')pA(3',5')p]], MIW815, ML RR-S2 CDA, S100
AF12198 Immunopharmacology Ligand 4861 AF 12198, AF-12198
AFM13 Immunopharmacology Ligand 10067 AFM 13, AFM-13
agatolimod Immunopharmacology Ligand 9843 CpG 7909, CpG7909, PF 3512676, PF-3512676, ProMune, VaxImmune
AH10-7 Immunopharmacology Ligand 9899
AH6809 Immunopharmacology Ligand 1896 AH 6809, AH-6809
AL-78898A Immunopharmacology Ligand 9219 4(1MeW), POT-4
alcaftadine Approved drug Immunopharmacology Ligand 7587 Lastacaft®, R-89674
alefacept Approved drug Immunopharmacology Ligand 6787 Amevive®, BG 9273, BG 9712, BG-9273, BG-9712, Lfa3Tip
alemtuzumab Approved drug Immunopharmacology Ligand 6770 campath 1H, Campath®, campath-1H, Lemtrada®
alimemazine Approved drug Immunopharmacology Ligand 7237 Nedeltran®, trimeprazine
3 alpha-aminocholestane Immunopharmacology Ligand 9564 3AC, 3 α-aminocholestane
ALT-803 Immunopharmacology Ligand 9615 IL-15 N72D:IL-15RαSu/Fc, IL-15SA, N-803
alvelestat Immunopharmacology Ligand 6476 AZD 9668, AZD-9668, AZD9668, KB-105160
AM-461 Immunopharmacology Ligand 10170 AM461, Compound 1 [WO2011085033]
AM-6120 Immunopharmacology Ligand 10119 AM6120, peptide 41 [PMID: 30346167]
amcinonide Approved drug Immunopharmacology Ligand 7060 CL-34699, Cyclocort®
amelubant Immunopharmacology Ligand 8463 BIIL 284, BIIL-284
AMG319 PDB Ligand Immunopharmacology Ligand 8917 AMG 319, AMG-319
AMG820 Immunopharmacology Ligand 9106
aminopyridine 2 Immunopharmacology Ligand 10051
amiselimod Immunopharmacology Ligand 9319 Example 1 [US20090137530], MT-1303, MT1303
amiselimod phosphate Immunopharmacology Ligand 9491 amiselimod-P, MT-1303-P
amlexanox Approved drug PDB Ligand Immunopharmacology Ligand 7113 AA-673, Amlexanox®, Aphthasol®, CHX-3673
amphiregulin  {Sp: Human} Immunopharmacology Ligand 4864 colorectal cell-derived growth factor (CRDGF)
AMT-101 Immunopharmacology Ligand 11645
AMY109 Immunopharmacology Ligand 12789 AMY-109, H1009/L395-F1974m
anakinra Approved drug Immunopharmacology Ligand 6972 antril, Kineret®
anatumomab mafenatox Immunopharmacology Ligand 9947 5T4FabV13SEAD227A, ABR 214936, ABR-214936, ABR214936, pMB125, PNU 214936, PNU-214936, PNU214936, TTS-CD2
ancriviroc Immunopharmacology Ligand 804 SCH 351125, SCH-351125, SCH-C
andecaliximab Immunopharmacology Ligand 9510 GS-5745, GS5745
andrographolide Immunopharmacology Ligand 9675
anifrolumab Approved drug Immunopharmacology Ligand 8258 anifrolumab-fnia, MDX-1333, MEDI-546, Saphnelo®
apafant Immunopharmacology Ligand 1860 WEB 2086 BS, WEB-2086
apilimod Immunopharmacology Ligand 9859 LAM-002A (apilimod dimesylate), LAM002A, STA 5326, STA-5326, STA5326
apratastat Immunopharmacology Ligand 6482 compound 5h [PMID: 16426848], TMI-05, TMI005
apremilast Approved drug PDB Ligand Immunopharmacology Ligand 7372 CC-10004, Otezla®
APRIL  {Sp: Human} Immunopharmacology Ligand 5068 A proliferation-inducing ligand, TALL2, TNF- and APOL-related leukocyte expressed ligand 2, TNF-related death ligand 1, TRDL-1, ZTNF2
arformoterol Approved drug PDB Ligand Immunopharmacology Ligand 7479 Brovana®, YM-08316
ARN19702 PDB Ligand Immunopharmacology Ligand 10120 ARN-19702, compound 8 [PMID: 27404798]
ARN726 Immunopharmacology Ligand 9178 ARN-726, compound 6 [PMID: 25874594]
(R)-ARN2508 Immunopharmacology Ligand 9000 compound (-)-10r [PMID: 26774927], example 19 [WO2014023643]
(S)-ARN2508 PDB Ligand Immunopharmacology Ligand 8999 compound (+)-10r [PMID: 26774927], example 20 [WO2014023643]
arpromidine Immunopharmacology Ligand 1221 ARP
ARRY-371797 Immunopharmacology Ligand 11095 ARRY-797, ARRY371797, ARRY797, compound 7 [PMID: 19950901]
ARRY-382 Immunopharmacology Ligand 9108 ARRY 382, ARRY382, c-Fms-IN-12, PF-07265804, PF07265804
ARRY-502 Immunopharmacology Ligand 10179 ARRY502, example 237, enantiomer 1 [WO2009158426A1]
AS101 Immunopharmacology Ligand 437 ammonium tri-chloro(dioxoethylene-O,O'-)tellurate, AS 101, AS-101
AS-252424 Immunopharmacology Ligand 10578 AS252424, compound 26 [PMID: 16789742]
asapiprant Immunopharmacology Ligand 11951 BGE-175, BGE175, example II-74 [US8153793B2], S-555739
asimadoline Immunopharmacology Ligand 9279 EMD 61 753, EMD 61753, EMD-61753
asivatrep Immunopharmacology Ligand 9621 Example 230 [US7858621], PAC-14028
ASP4058 Immunopharmacology Ligand 9569 ASP-4058
aspirin Approved drug PDB Ligand Immunopharmacology Ligand 4139 Acetophen®, acetylsalicylic acid, Aspirin®
aspirin-triggered resolvin D1 Immunopharmacology Ligand 6239 AT-Resolvin D1, AT-RvD1
AT38 Immunopharmacology Ligand 9020 [3-(aminocarbonyl)furoxan-4-yl]methyl salicylate
atacicept Immunopharmacology Ligand 9517 TACI-Fc, TACI-Ig
atezolizumab Approved drug Immunopharmacology Ligand 7990 MPDL3280A, Tecentriq®
ATI-50001 Immunopharmacology Ligand 12317 ATI-501, ATI50001, ATI501, example 103 [WO2007070872A1]
atibuclimab Immunopharmacology Ligand 11326 IC14
atracurium Approved drug Immunopharmacology Ligand 9537 atracurium besilate, atracurium dibesylate, BW 33A, Tracrium®
auranofin Approved drug Immunopharmacology Ligand 6306 Ridaura®, SK&F-39162, SK-39162
avacopan Approved drug PDB Ligand Immunopharmacology Ligand 9450 CCX-168, CCX168, Tavneos®
avadomide Immunopharmacology Ligand 10522 CC-122, CC122, Compound A [WO2014039960A1]
avapritinib Approved drug Immunopharmacology Ligand 10368 Ayvakit®, Ayvakyt®, BLU-285, BLU285
avdoralimab Immunopharmacology Ligand 11345 anti-hC5aR-32F3A6 GL, IPH-5401, NN-8210, NNC-0215-0384
AVE 0991 Immunopharmacology Ligand 5579 AVE-0991, AVE0991
avelumab Approved drug Immunopharmacology Ligand 8735 Bavencio®, MSB-0010718C, MSB0010718C
AX-024 Immunopharmacology Ligand 11253 AX-24, AX024
AZ13102909 Immunopharmacology Ligand 9577 AZ909
AZ2 PDB Ligand Immunopharmacology Ligand 10233
AZ3451 PDB Ligand Immunopharmacology Ligand 9560
AZ7188 Immunopharmacology Ligand 9586
AZ8838 PDB Ligand Immunopharmacology Ligand 9585
azacitidine Approved drug PDB Ligand Immunopharmacology Ligand 6796 5-AZAC, 5-azacytidine, ladakamycin, Onureg®, Onureg® (CC-486; oral azacitidine), U-18496, Vidaza®
azapro-3 Immunopharmacology Ligand 9221
azatadine Approved drug Immunopharmacology Ligand 7119 Optimine®, SCH-10649
azathioprine Approved drug Immunopharmacology Ligand 7120 Azasan®, BW-57-322, Imuran®, Jayempi®
AZD0284 PDB Ligand Immunopharmacology Ligand 11711 AZD-0284, compound 20 [PMID: 34464130]
AZD1236 Immunopharmacology Ligand 7844 AZD 1236, AZD-1236
AZD1678 Immunopharmacology Ligand 9679 AZD-1678, compound 49 [PMID: 28947948]
AZD1981 Immunopharmacology Ligand 7680 AZD 1981, AZD-1981
AZD2098 Immunopharmacology Ligand 9678 AZD-2098, compound 47 [PMID: 28947948]
AZD2423 Immunopharmacology Ligand 7825 AZD 2423, AZD-2423
AZD3458 Immunopharmacology Ligand 9997 AZD-3458, compound 15 [PMID: 29852070]
AZD3965 Immunopharmacology Ligand 10605 AZD-3965
AZD5069 Immunopharmacology Ligand 8948 AZD-5069
AZD5423 PDB Ligand Immunopharmacology Ligand 13017 AZD-5423, compound 1b [PMID: 28937774]
AZD5672 Immunopharmacology Ligand 7686 AZD 5672, AZD-5672
AZD5718 Immunopharmacology Ligand 10352 compound 12 [PMID: 30869888]
AZD6605 Immunopharmacology Ligand 7823 AZ 11920155, AZ-11920155, AZ11920155, AZD 6605, AZD-6605
AZD6703 PDB Ligand Immunopharmacology Ligand 7687 AZ 12012199, AZ-12012199, AZ12012199, AZD 6703, AZD-6703
AZD7624 Immunopharmacology Ligand 11714 AZD-7624, Example 259 [WO2009001132]
AZD8154 PDB Ligand Immunopharmacology Ligand 11204 AZD-8154, Example 1 [WO2018055040A1]
AZD8848 Immunopharmacology Ligand 9256 DSP-3025
AZD9056 Immunopharmacology Ligand 7826 AZD 9056, AZD-9056
AZD9567 PDB Ligand Immunopharmacology Ligand 9812 AZD 9567, AZD-9567, compound 15 [PMID: 29424542], example 1 [WO2016046260A1]
AZD9898 Immunopharmacology Ligand 10479 AZD-9898, example 62 [WO2016177845A1]
azelaic acid Approved drug PDB Ligand Immunopharmacology Ligand 7484 Azelex®, Finacea®, ZK-62498
azithromycin Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6510
AZ11657312 (salt free) Immunopharmacology Ligand 7722
 
B Back to top
bafetinib PDB Ligand Immunopharmacology Ligand 7906 INNO-406, Lyn-IN-1, NS-187
BAFF  {Sp: Human} Immunopharmacology Ligand 5069 B cell-activating factor, CD257 antigen, dendritic cell-derived TNF-like molecule
balamapimod Immunopharmacology Ligand 9925 MKI-833, MKI833
bardoxolone Immunopharmacology Ligand 2717 CDDO, RTA-401
baricitinib Approved drug PDB Ligand Immunopharmacology Ligand 7792 INCB-028050, INCB028050, LY-3009104, LY3009104, Olumiant®
basiliximab Approved drug Immunopharmacology Ligand 6879 CHI-621, L04AC02, SDZ-CHI-621, Simulect®
BAY 11-7082 Immunopharmacology Ligand 5934 (E)-3-tosylacrylonitrile, BAY-117082, BAY117082
BAY-985 Immunopharmacology Ligand 10597 BAY985, compound 34 [PMID: 31859507]
BAYu9773 Immunopharmacology Ligand 3381 BAY u9773, BAY-u 9773
BC-1215 Immunopharmacology Ligand 12671 BC 1215, BC1215
beclometasone Approved drug PDB Ligand Immunopharmacology Ligand 7059 beclomethasone, SCH-18020W
beclometasone dipropionate Approved drug Immunopharmacology Ligand 5894 beclomethasone dipropionate, Beconase®, Qnasl®, Vancenase®
begelomab Immunopharmacology Ligand 8691 Begendina&rg; (proprietary name), BT 5/9, SAND 26
belantamab mafodotin Approved drug Immunopharmacology Ligand 11117 belamaf, belantamab mafodotin-blmf, Blenrep®, GSK-2857916, GSK2857916
belatacept Approved drug Immunopharmacology Ligand 6892 BMS-224818, LEA29Y, Nulojix®
belimumab Approved drug Immunopharmacology Ligand 6887 Benlysta®, hBlySmAb-1.1, LimphoStat-B, lymphostat-B
belnacasan Immunopharmacology Ligand 9035 HMR3480, VX-765
belumosudil Approved drug PDB Ligand Immunopharmacology Ligand 9558 KD-025, KD025, Rezurock®, SLx 2119, SLx2119
bempegaldesleukin Immunopharmacology Ligand 10659 NKTR-214, NKTR214
benralizumab Approved drug Immunopharmacology Ligand 7674 BIW-8405, Fasenra®, KHK4563, MEDI-563
bentamapimod Immunopharmacology Ligand 9926 AS-602801, AS602801, PGL-5001, PGL5001
benzodrocortisone Immunopharmacology Ligand 9731 compound 1 [WO2013071010], hydrocortisone 17-benzoate
3beta-Hydroxy-20(29)-lupene Immunopharmacology Ligand 9028 Fagarasterol, Lupeol
betamethasone Approved drug Immunopharmacology Ligand 7061 SCH-4831
bexmarilimab Immunopharmacology Ligand 12907 Clevegen, FP-1305, FP1305
BI-1935 Immunopharmacology Ligand 9717 BI 1935, example 3 [WO2007067836]
BI-1950 Immunopharmacology Ligand 9719
BI-2545 PDB Ligand Immunopharmacology Ligand 9791 BI2545, compound 19 [PMID: 29259743]
BI605906 Immunopharmacology Ligand 9357 3-Amino-4-(1,1-difluoro- propyl)-6-(4-methanesulfonyl- piperidin-1-yl)-thieno[2,3- b]pyridine-2-carboxylic acid amide, compound 115 [US20070293533]
BI 653048 Immunopharmacology Ligand 9715 (R)-39, BI 653048 BS H3PO4, BI-653048, BI653048
BI 665915 Immunopharmacology Ligand 9716 BI-665915, compound 69 [PMID: 25671290]
BI-6901 Immunopharmacology Ligand 9714 BI 6901, BI 6901, BI6901, eut-22
bifikafusp alfa Immunopharmacology Ligand 9756 Darleukin, L19-IL2, L19IL2
bihelical apoA-I mimetic peptide 5A Immunopharmacology Ligand 9183 5A peptide
BIIB068 PDB Ligand Immunopharmacology Ligand 11178 BIIB-068, compound 1 [PMID: 32696648]
bimekizumab Approved drug Immunopharmacology Ligand 9411 bimekizumab-bkzx, Bimzelx®, CA028_0496, CDP4940, gL7gH9, UCB-4940, UCB4940, Zu-G1
bimosiamose Immunopharmacology Ligand 9049 compound 15e [PMID: 9544210], TBC 1269, TBC-1269, TBC1269
bindarit Immunopharmacology Ligand 11124 AF-2838, AF2838
BIRT 377 Immunopharmacology Ligand 9720 BIRT-377
blinatumomab Approved drug Immunopharmacology Ligand 7384 Blincyto®, bscCD19xCD3, MEDI-538, MT-103, MT103
blisibimod Immunopharmacology Ligand 9518 A-623, AGP3 peptibody, AMG 623, Fc-Agp-3
BML-281 Immunopharmacology Ligand 9664 compound 3 [PMID: 18642892]
BMS-1001 Immunopharmacology Ligand 10191 BMS1001, Example 1001 [WO2015160641A2]
BMS-1166 Immunopharmacology Ligand 9608 compound 2c [PMID: 28613862], Example 1166 [WO2015160641A2]
BMS-202 PDB Ligand Immunopharmacology Ligand 9607 compound 1c [PMID: 28613862], PD1-PDL1 inhibitor 2
BMS-345541 Immunopharmacology Ligand 5669 BMS 345541, BMS345541
BMS-509744 Immunopharmacology Ligand 9994 BMS 509744, BMS509744, compound 3 [PMID:16682193]
BMS-561392 Immunopharmacology Ligand 6509 BMS 561392, BMS561392, DPC-333
BMS-582949 PDB Ligand Immunopharmacology Ligand 7838 BMS 582949, BMS582949, PS 540446, PS-540446, PS540446
BMS-681 PDB Ligand Immunopharmacology Ligand 9430 compound 13d [PMID: 25893046]
BMS-817399 PDB Ligand Immunopharmacology Ligand 9497 compound 29 [PMID: 25101488]
BMS-986142 PDB Ligand Immunopharmacology Ligand 9857 BMS986142, compound 14f [PMID: 27583770]
BMS-986166 Immunopharmacology Ligand 11493 BMS986166, compound 14a [PMID: 30785748]
BMS-986235 Immunopharmacology Ligand 11024 BMS986235, compound 13c [PMID: 32407089], LAR-1219, LAR1219
BMS-986260 PDB Ligand Immunopharmacology Ligand 10662 BMS986260, compound 10 [Velaparthi et al., 2020], Example 32' [WO2016140884A1]
BMS-986104 derivative 12 Immunopharmacology Ligand 11494 compound 12 [PMID: 33492963]
BMS-986104 derivative 24 Immunopharmacology Ligand 11495 compound 24 [PMID: 33492963]
bortezomib Approved drug PDB Ligand Immunopharmacology Ligand Antimalarial Ligand 6391 peptide boronate, PS-341, Velcade®
bosutinib Approved drug PDB Ligand Immunopharmacology Ligand 5710 Bosulif®, SK 606, SK-606, SKI 606
branebrutinib Immunopharmacology Ligand 9869 BMS-986195, BMS986195, Example 223 [US20160115126A1]
brazikumab Immunopharmacology Ligand 9293 AMG 139, AMG-139, MEDI2070
brensocatib Immunopharmacology Ligand 9412 AZD7986, compound 30, INS 1007, INS1007
brentuximab vedotin Approved drug Immunopharmacology Ligand 6772 Adcetris®, anti-CD30 ADC SGN-35, SGN 35
brepocitinib PDB Ligand Immunopharmacology Ligand 10459 compound 23 [PMID: 30113844], PF-06700841, PF06700841
briakinumab Immunopharmacology Ligand 9213 ABT-874, J-695, J695, Ozespa
brimapitide Immunopharmacology Ligand 9101 AM-111, D-JNKI-1, XG-102
brimonidine Approved drug PDB Ligand Immunopharmacology Ligand 520 Alphagan®, Lumify®, Mirvaso®, UK14,304, UK14304
BRL-15572 Immunopharmacology Ligand 10 BRL 15572, BRL-15,572, BRL15572
brodalumab Approved drug Immunopharmacology Ligand 7540 AMG-827, AMG827, Kyntheum®, Lumicef®, Siliq®
bromfenac Approved drug PDB Ligand Immunopharmacology Ligand 7131 AHR-10282B, Bromday®, Prolensa®, Xibrom®
BsAb (CD89-CD20) Immunopharmacology Ligand 9833
BT-11 Immunopharmacology Ligand 10363 analogue 7 [PMID: 27933891], BT11, Example 1 [US9556146B2]
BT7480 Immunopharmacology Ligand 12060 BCY11863, BT-7480
BTP2 Immunopharmacology Ligand 2438 YM-58483
budesonide Approved drug Immunopharmacology Ligand 7434 Entocort®, Eohilia® (budesonide oral suspension), Jorveza®, Pulmicort®, S-1320, Uceris®
butyric acid